Nicholas J. Schisler, PhD

Refereed Publications

*indicates student authors.

Schisler, N.J. and Singh, S.M. Determinants and distribution of the enzymes which detoxify oxygen free radicals in mice and their possible role in chromosomal breaks. (in preparation)

Schisler, N.J. and Singh, S.M. The molecular evolution of the glutathione peroxidase gene family.(in preparation)

Ambrose, S.*, Carpenter, A.*, Black, K.*, Reiner, A.*, Singh, S.M., and Schisler, N.J. The molecular evolution of the regulation of the catalase gene in Mus musculus. (in preparation)

Lynes, J.*, Gillman, R.*, Singh, S.M., and Schisler, N.J. 2005. Amyotrophic lateral sclerosis and Cu-Zn superoxide dismutase mutations. (in preparation)

Gillman, R. *, Bruett, A.*, Devendra, G.,* Kurwa, A.,* Lizama-Price, A.,* Maund, S., Tancaktiong, G., Stoltzfus A., and Schisler, N.J. 2005. Genome streamlining in evolution: the contribution of intron sequences. (in preparation)

Gillman, R.*, Bruett, A.*, Devendra, G.,* Kurwa, A.,* Lizama-Price, A.,* Maund, S., Tancaktiong, G., Stoltzfus A., and Schisler, N.J. 2005. The phylogenetic distribution of spliceosomal introns. (in preparation)

Qiu WG, Schisler N, Stoltzfus A. 2004. The evolutionary gain of spliceosomal introns: sequence and phase preferences. Molecular Biology and Evolution 21(7):1252-63.
Erratum in: Mol Biol Evol. 2004 Sep;21(9):1812.

Schisler, N.J. and Palmer, J.D. 2000. The IDB and IEDB: intron sequence and evolution databases.
Nucleic Acids Research. 28: 181-184

Celerin, M., Gilpin, A.A., Schisler, N.J., Ivanov, A.G., Miskiewicz, E., Krol, M. and Laudenbach, D.E . 1998.
ClpB in a cyanobacterium: predicted structure, phylogenetic relationships, and regulation by light and temperature. J
Journal of Bacteriology. 180: 5173-5182.

Celerin, M., Ray, J.M., Schisler, N.J., Day, A.W., Stetler-Stevenson, W.G. and Laudenbach, D.E. 1996.
Fungal fimbriae are composed of collagen. EMBO Journal. 15: 4445-4453.

Hill, K.A., Schisler, N.J. and Singh, S.M. 1992. Chaos game representation of coding regions of human
globin genes and alcohol dehydrogenase of phylogenetically divergent species. Journal of Molecular Evolution. 35: 261-269.

Schisler, N.J. and Singh, S.M. 1990. A quantitative genetic analysis of catalase activity in Mus musculus.
Biochemical Genetics. 29: 65-89.

Schisler, N.J. and Singh, S.M. 1989. Effect of ethanol in vivo on enzymes which detoxify oxygen free radicals.
Free Radical Biology and Medicine. 7: 117-123.

Schisler, N.J. and Singh, S.M. 1988. Modulation of selenium-dependent glutathione peroxidase (Se-GSH-Px) activity in mice.
Free Radical Biology and Medicine. 4: 147-153.

Schisler, N.J. and Singh, S.M. 1987. Inheritance and expression of tissue-specific catalase activity during development
and aging in mice. Genome. 29: 748-760.

Schisler, N.J. and Singh, S.M. 1985.Tissue specific developmental regulation of superoxide dismutase
(SOD-1 and SOD-2) activities in genetic strains of mice. Biochemical Genetics. 23: 289-306.

Conference Abstracts

* indicates student researcher.

McCaman, R., Kataoka, A.*, Francis, R.,* Le, A.*, Acheson, P.*, Chan, D.,* Shin, K-S.,* Ryu, T., Chang, W.Y.,
Eernisse, D., and Schisler, N. 2002. Blasting the exons out of introns. Intelligent Systems for Molecular Biology. Edmonton
Alberta, Canada

McCaman, R., Ryu, T.W., Chang, W.Y., Eernisse, D., Akitake, B.,* Bruett, A.*, Kurwa, A.,* Lizama-Price, A.,* Tancaktiong, G.,*
and Schisler, N. 2002. Going, Going....Gone - Intron Streamlining in Complex Eukaryotic Genomes. Intelligent Systems for Molecular
Biology. Edmonton, Alberta, Canada

McCaman, R., Ryu, T.W., Chang, W.Y., Eernisse, D., Akitake, B.*, Bruett, A.,* Kurwa, A.,* Lizama-Price, A.*, Tancaktiong, G.*, and
Schisler, N. 2002. Intron Sequence Conservation in Complex Eukaryotic Genomes. Intelligent Systems for Molecular Biology. Edmonton,
Alberta, Canada

Schisler, N.J., Gordon, S.M.* and Singh, S.M. 1996. The use of sequence profiles in the identification of distantly related proteins. Canadian Workshop on Computational Biology. University of Western Ontario. London, Ontario Canada N6A 5B7.

Schisler, N.J., Gordon, S.M.* and Singh, S.M. 1995. Familial amyotrophic lateral sclerosis (FALS) associated mutations and sequence divergence during the evolution of the human superoxide dismutase genes. American Society of Human Genetics Meeting. Philadelphia, PA USA.

Hill, K.A., Schisler, N.J. and Singh, S.M. 1992. Examination of DNA sequence structure using chaos game theory. Western Research Forum. University of Western Ontario. London, Ontario Canada N6A 5B7.

Reimer, D.L., Schisler, N.J. and Singh, S.M. 1991. Molecular studies on the regulation of murine catalase gene expression and acatalasemia. American Journal of Human Genetics 4: 460.

Hill, K.A., Schisler, N.J. and Singh, S.M. 1991. The alcohol dehydrogenase (ADH) multigene family as a model for analysis of eukaryotic gene regulation and evolutionary mechanisms. American Journal of Human Genetics 4: 460.

Hill, K.A., Schisler, N.J. and Singh, S.M. 1991. Selective substitution and codon bias in the evolution of alcohol dehydrogenase (ADH) genes. Canadian Federation of Biological Sciences Meeting. Kingston, Ontario Canada.

Schisler, N.J. and Singh, S.M. 1988. Genetic variability in the oxygen radical metabolizing enzymes: a quantitative study of enzyme activity, mRNA levels and DNA polymorphism. Genome 30: 181 (Suppl. 1).

Schisler, N.J. and Singh, S.M. 1986. Relative variability in the activity of the oxygen radical metabolizing enzymes in mice: a quantitative approach to evaluate selection at the level of the enzyme. Genetics Society of Canada Bulletin 17: 107.

Schisler, N.J. and Singh, S.M. 1985. Trans-acting genetic regulation of tissue-specific catalases during development in mice. Genetics Society of Canada Bulletin 16: 44.

Schisler, N.J. and Singh, S.M. 1984. Regulatory aspects of oxygen derived free radical metabolizing enzymes. American Journal of Human Genetics 36: 185.

Invited Seminars and Workshops

Schisler, N.J. 2003. Bioinformatics, Introns and Evolution. Department of Biology, Furman University. Greenville, S.C. USA 29613

Schisler, N.J. 2002. Implications of the Human Genome Project. Family Weekend Lecture. Pomona College, Claremont, CA USA 91711.

Schisler, N.J. 2001. Teaching and technology: What Really Works. Teaching and Learning Center, Pomona College, Claremont, CA USA 91711.

Schisler, N.J. 2000. Intron Databases and their Application to Evolutionary Analysis. Center for Advanced Research in Biotechnology. National Institute of Standards. 9600 Gudelsky Dr., Rockville, MD USA 20850

Schisler, N.J. 2000. Databases, Introns and Evolution. Department of Biology, Pomona College. Claremont, CA USA 91711

Schisler, N.J. 2000. Bioinformatics: Methods, Applications and Challenges. Department of Biology, Pomona College. Claremont, CA USA 91711

Schisler, N.J. 1997. Trends in Bioinformatics. Departments of Biology and Chemistry, Indiana University Midwestern Web Science Workshop. Bloomington, IN USA 47405-6801.

Schisler, N.J. 1997. Biology Software Workshop. Departments of Biology and Chemistry, Indiana University Midwestern Web Science Workshop. Bloomington, IN USA 47405-6801.

Schisler, N.J. 1997. Mac Optimization and Buying Mac Hardware on a Budget. Departments of Biology and Chemistry, Indiana University Midwestern Web Science Workshop. Bloomington, IN USA 47405-6801.

Schisler N.J. 1996. Computers in Molecular Biology Research. Department of Zoology, University of Western Ontario. London, Ontario Canada N6A 5B7.

Send mail to nicholas.schisler@furman.edu with questions or comments about this web site.
Copyright © 1997-2005 Nicholas Schisler, PhD
Last modified: June 10, 2005